Hypoparathyroidism and pseudohypoparathyroidism
نویسندگان
چکیده
منابع مشابه
Hypoparathyroidism and pseudohypoparathyroidism.
The principal function of the parathyroid hormone (PTH) is maintenance of calcium plasmatic levels, withdrawing the calcium from bone tissue, reabsorbing it from the glomerular filtrate, and indirectly increasing its intestinal absorption by stimulating active vitamin D (calcitriol) production. Additionally, the PTH prompts an increase in urinary excretion of phosphorus and bicarbonate, seeking...
متن کاملHypoparathyroidism and pseudohypoparathyroidism: etiology, laboratory features and complications.
Objectives To identify a clinical profile and laboratory findings of a cohort of hypoparathyroidism patients and determine the prevalence and predictors for renal abnormalities. Materials and methods Data from medical records of five different visits were obtained, focusing on therapeutic doses of calcium and vitamin D, on laboratory tests and renal ultrasonography (USG). Results Fifty-five...
متن کاملPseudohypoparathyroidism: A Variation on the Theme of Hypoparathyroidism
Pseudohypoparathyroidism is characterized by an inability of the body to respond appropriately to parathyroid hormone (PTH), the principal hormone that regulates calcium and phosphorous levels in the body. PTH is made by the parathyroid glands in the neck. There are usually four parathyroid glands, but we probably only need one or two of the glands. PTH is missing, or too low, in patients with ...
متن کاملEffects of active vitamin D3 and parathyroid hormone on the serum osteocalcin in idiopathic hypoparathyroidism and pseudohypoparathyroidism.
Serum osteocalcin was measured in patients with idiopathic hypoparathyroidism or pseudohypoparathyroidism, before or during the treatment with active vitamin D3 (1,25(OH)2D3 or 1 alpha OHD3). Serum osteocalcin and plasma 1,25(OH)2D were decreased in 11 patients with idiopathic hypoparathyroidism before treatment (2.8 +/- 1.27 ng/ml, P less than 0.001 and 14.3 +/- 4.27 pg/ml, P less than 0.001, ...
متن کاملGNAS locus and pseudohypoparathyroidism.
Pseudohypoparathyroidism (PHP) is characterized by hypocalcemia and hyperphosphatemia due to resistance to parathyroid hormone (PTH). Patients with PHP-Ia often present with additional hormonal resistance and show characteristic physical features that are collectively termed Albright's hereditary osteodystrophy (AHO). These features are also present in pseudopseudohypoparathyroidism (PPHP), but...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arquivos Brasileiros de Endocrinologia & Metabologia
سال: 2006
ISSN: 0004-2730
DOI: 10.1590/s0004-27302006000400012